Effect of Cannabinoids and Cannflavins on Neurodegeneration, Lifespan, and Healthspan - Hunter Land скачать в хорошем качестве

Effect of Cannabinoids and Cannflavins on Neurodegeneration, Lifespan, and Healthspan - Hunter Land

Tags: Cannabidiol, Cannabigerol, Cannflavins, C. elegans, CBD, CBG, Cannabis Research Hunter Land, PhD, presents "Effect of Cannabinoids and Cannflavins on Neurodegeneration, Lifespan, and Healthspan" at CannMed 23. 0:00 Intro 0:22 Disclosures 0:35 Outline 1:46 C. elegans model 2:58 C. elegans and Cannabidiol - Lifespan 4:02 C. elegans and Cannabidiol - Healthspan 4:57 C. elegans and Cannabigerol - Lifespan 5:45 C. elegans and Cannabigerol - Healthspan 6:12 C. elegans Tau Model 7:30 C. elegans Tau Tau Study Design 9:57 Survival - C. elegans model 10:22 Survival - Cannflavins 11:01 Survival - Cannabinoid BDS 11:20 Survival - Cannabinoid BDS 11:52 Survival - Cannabinoid BDS + Cannflavin 12:50 Activity Levels - C. elegans Model 13:50 Conclusion 14:40 Q&A Many neurodegenerative diseases and conditions associated with neuronal insult are characterized by intracellular aggregates of the microtubule associated protein Tau. Some compounds found in cannabis have previously demonstrated the ability to extend lifespan and improve healthspan parameters in the model organism Caenorhabditis elegans but the impact on Tau-induced neurodegeneration remains unknown. The recent development and validation of the BR5270 transgenic C. elegans strain exhibits accelerated Tau aggregation, severely impaired motility as a result of neuronal dysfunction, and a shortened lifespan compared to wild-type controls. Due to the significant impact on lifespan and locomotion defect produced by this model, time/cost-effective and high throughput acquisition of data, the C. elegans model of tauopathy serves as an advantageous screening tool for the discovery of novel modulators of neurodegeneration. Learn More about CannMed: https://cannmedevents.com/