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What medications are opioids Key PointsPrescription opioids also called narcotics or pain killers are a large class of drugs and an important part of modern medical care Common prescription opioids available in the US include codeine fentanyl hydrocodone morphine oxycodone and tramadol Painkillers as a class are also called narcotic analgesicsOpioids may be used shortterm to ease the discomfort from conditions such as a broken bone or after surgery or for longterm pain such as cancer Opioids are also used in cough medications codeine or hydrocodone in medicines for diarrhea and even to help combat opioid addiction itself They can also be used in combination with other medications such as acetaminophen or ibuprofen for added pain reliefAll opioids are chemically related and work in concert with opioid receptors on nerve cells in the body and central nervous system Some opioids are stronger than others but over time you can develop a tolerance to them and may need higher doses to be effective for the same level of painMisuse of opiates can lead to dependence addiction and in some situations overdose which can be fatal According to the National Institute on Drug Abuse NIDA over Americans died from druginvolved overdose in including illicit drugs and prescription opioids Because of this risk as well as the risk of diversion these drugs are classified as controlled substances in the USRelated Understanding Opioid Narcotic Pain MedicationsExamples of prescription opioidsSome of the most common single agent opioids prescribed for pain in the US includecodeine sulfatefentanyl Actiq Duragesic Fentora Lazanda Sublimaze Subsyshydrocodone Hysingla ER Zohydro ERhydromorphone Dilaudidmorphine Kadian MS Continoxycodone Oxaydo OxyContin Roxicodone Xtampza ERoxymorphonetramadol Conzip Qdolo UltramNarcotic analgesic combinations contain an opioid with another class of analgesic such as acetaminophen ibuprofen or aspirin They are used to treat moderate to severe pain Common examples includeaspirin butalbital caffeine and codeine Fiorinal with Codeineacetaminophen butalbital caffeine and codeine Fioricet with Codeineacetaminophen and oxycodone Oxycet Percocethydrocodone and ibuprofenacetaminophen and hydrocodone Lortab Lorcet Norco Vicodinacetaminophen caffeine and dihydrocodeine Trezixacetaminophen and tramadol Ultracetnaloxone and pentazocineaspirin and oxycodone Percodanacetaminophen and codeineacetaminophen caffeine and dihydrocodeine TrezixTo see a full list of prescription opioids visit these Drugscom pagesNarcotic analgesics single agents in more detailNarcotic analgesic combination agents in more detailRelated questions Meloxicam vs Ibuprofen Whats the difference Aleve vs Ibuprofen Whats the difference Naproxen vs ibuprofen Whats the difference Are opioids safePrescription opioids are usually safe when used as directed and for short periods of time as directed by your healthcare provider Due to the risk of abuse doctors only prescribe these drugs when other pain treatments such as nonopioid pain medicines like acetaminophen or NSAIDs do not adequately treat your pain or you cannot take these medications due to side effects allergies or other problemsEven when prescribed correctly by a doctor some people will take them for longer than prescribed use larger quantities abuse them by taking with alcohol or other drugs or sell or give them to people illegally Opioids are frequently misused because they cause euphoria or a high and relaxation in addition to the pain relief effectNot all opioids are prescription drugs Heroin is considered a highly addictive and illegal opiate drug and is classified as a Schedule I drug under the Controlled Substances Act of Heroin carries strong criminal penalties and has no accepted medical use in the United States as determined by the DEARelated Heroin information on DrugscomIf you suspect someone is having an overdose call or other emergency personnel immediately Signs of an opioid overdose includeextreme drowsinessblue lips and fingernailsslow or halted breathingpinpoint pupilsslow heart ratecomadeathIn case of an opioid overdose individuals who take opioids or their caregivers should always have a rescue medication called naloxone Narcan within reach This medication can block the effects of opiates to help reverse an overdose an opioid antagonist You should still call for emergency help and more than one dose of naloxone may need to be administeredEffective medicines are also available that are used to treat opioid use disorders and addiction including buprenorphine a partial opioid agonistantagonist methadone an opioid agonist and naltrexone an opioid antagonistThis is not all the information you need to know about opioids or related medicin