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Heart failure is a complex chronic condition impacting many patients in the US and around the world. We have gotten much better at diagnosing and treating heart failure, but it continues to have a high mortality, with a 5 year survival of around 50%. The pathophysiology of heart failure can be complex, but it is crucial to understand it if you are going to see patients with the condition. In this video we discuss the pathophysiology including to relationship with the kidneys and nervous system. Future videos will discuss specific treatments of heart failure with reduced vs preserved ejection fraction. This video is intended to be at the level of 4th year medical student and internal medicine resident. #heartfailure #cardiology #medicine 00:00 Intro 00:45 Definition 01:16 Epidemiology 03:08 Causes and Risk Factors 04:56 Subtypes and Ejection Fraction 07:15 Pathophysiology 12:54 Electrophysiology 13:34 Hemodynamics and Decompensation 16:49 Patient History 18:05 NYHA Staging 19:09 Physical Exam 21:34 Lab Testing 23:14 Chest X-ray 24:48 Echocardiogram 26:03 Other Imaging 26:29 Outro References: Harrison's Internal Medicine 21st Ed. https://www.cdc.gov/heart-disease/abo... https://www.totalcardiaccare.com/risk... https://www.researchgate.net/publicat... https://www.cambridge.org/core/books/... https://emsbasics.com/2011/10/17/what...