Neurofibromas Seen in Neurofibromatosis ; Cutaneous, Subcutaneous, Plexiform Neurofibromas скачать в хорошем качестве

Neurofibromas Seen in Neurofibromatosis ; Cutaneous, Subcutaneous, Plexiform Neurofibromas

Neurofibromas are benign tumors that develop from the nerve sheath cells and are a hallmark of neurofibromatosis. There are three types of neurofibromatosis, each associated with different types of neurofibromas: Neurofibromatosis Type 1 (NF1) Cutaneous Neurofibromas: Small, benign tumors that appear on or under the skin. They usually start appearing during adolescence. Plexiform Neurofibromas: Larger, more complex tumors that involve multiple nerve bundles. These can cause significant disfigurement and functional impairment. Neurofibromatosis Type 2 (NF2) Schwannomas: Benign tumors that develop from Schwann cells, which insulate nerve fibers. These often affect the auditory nerves, leading to hearing loss3. Schwannomatosis Schwannomas: Similar to NF2, but without the vestibular nerve involvement. These tumors can cause pain, numbness, and weakness2. Symptoms Cutaneous Neurofibromas: Small lumps under the skin, which can be itchy or painful. Plexiform Neurofibromas: Can cause significant pain, neurological deficits, and disfigurement. Schwannomas: Can lead to hearing loss, balance issues, and other neurological symptoms. Diagnosis and Treatment Diagnosis: Based on clinical examination, family history, and imaging studies. Treatment: Often involves surgical removal of tumors, pain management, and monitoring for malignant transformation #Neurofibromatosis #Neurofibroma