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The COPS trial aimed to assess the use of a cutting balloon technique in patients with calcified lesions. In this touchCARDIO interview, we speak with Dr Antonio Mangieri (Humanitas Research Hospital IRCCS, Rozzano, Milan, Italy) to discuss the challenges in treating patients with coronary artery calcifications and the outcome of the COPS trial. The abstract entitled ‘Cutting Balloon to Optimize Predilatation for Stent Implantation: The COPS Randomized Trial’ was presented at the Transcatheter Cardiovascular Therapeutics (TCT) conference, 16 – 19, September 2022. Questions: 1. What are the challenges of treating severely calcified lesions? (0:34) 2. What is the rationale for the use of a cutting balloon to optimise stent implantation? (1:24) 3. What were the aims, design and eligibility criteria of the COPS randomised trial? (2:05) 4. What were the efficacy and safety findings of the study? (2:38) 5. What were the strengths and limitations of the study? (4:41) Disclosures: Antonio Mangieri has nothing to disclose in relation to this video interview. Support: Interview and filming supported by Touch Medical Media. Interview conducted by Danielle Crosby. Filmed as a highlight of TCT 2022 (https://www.touchcardio.com/conferenc...) Access more content on: Devices here: https://www.touchcardio.com/specialit... Interventional Cardiology here: https://www.touchcardio.com/specialit...