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People abandon cancer treatment every day because the side effects are unbearable. The fatigue. The nausea. The brain fog that makes you feel like a stranger in your own life. And the dirty secret of oncology is that we have no idea if a lower dose would have worked just as well — because we never seriously looked. Dr. Andrea De Censi looked and changed lives for millions of women. A world-renowned researcher and the force behind low-dose tamoxifen, Dr. De Censi spent his career asking the question oncology was too comfortable to ask: what is the minimum dose that actually works? His findings didn't just challenge the standard of care — they changed treatment for millions of women. Now he's turning that same lens on metformin and what it might mean for the future of cancer prevention. This conversation will change how you think about every prescription you've ever been handed. In this episode: Why cancer dosing was built around maximum tolerance — not minimum effectiveness The research behind low-dose tamoxifen and what it means for side effect management What metformin's potential role in cancer care could mean for patients right now How to have the dosing conversation with your oncologist If you or someone you love is in treatment, in survivorship, or navigating cancer prevention — this one is not optional. 🎙️ Kicking Cancer's Ass is hosted by Joelle Kaufman — cancer survivor, author of Crushing the Cancer Curveball, and TEDx speaker. 🔔 Subscribe so you never miss an episode. 📩 Get the full article at kcapodcast.com Learn more about scalp cooling from episode sponsor - www.coldcap.com Learn more about UCSF RiseUp at https://riseup.ucsf.edu/ We never chose the pitch. But we always choose the swing.