#ABRF2025 скачать в хорошем качестве

#ABRF2025

Speakers: Ingrid Bergin Yuqing Eugene Chen, MD, PhD K.C. Kent Lloyd, DVM, PhD This speaker panel and discussion session will provide an overview of animal phenotyping core facilities. Animal phenotyping broadly refers to the descriptive or interpretive characterization of animal models, usually animal models of human disease. Phenotyping means different things in different contexts and core facilities offering these services are quite diverse. Examples include behavioral, physiologic, or metabolic phenotyping cores and animal tissue or molecular histopathology facilities. While mice are typically a major focus, phenotyping strategies have also been applied to other species. Challenges faced by staff and users of these facilities include reagent and methods challenges inherent to the diverse species and the need for broadly ranging expertise to address different aspects of phenotyping. In this session, Dr. Kent Lloyd, the director of the University of California-Davis Mouse Biology Program, will give an overview of the NIH-sponsored Mouse Metabolic Phenotyping Centers (MMPC-Live) and the Knockout Mouse Project (KOMP2), two large scale murine phenotyping efforts. Additionally, Dr. Yuqing Eugene Chen, director of the Center for Advanced Models For Translational Sciences and Therapeutics (CAMTraST) at the University of Michigan-Ann Arbor will describe the transgenic rabbit models generated by CAMTraST as examples of non-murine animal models. A panel discussion will also describe best practices for facilitating cross-disciplinary or cross-core collaborations in the context of animal models. Attendees will gain greater understanding of the diversity and scope of animal phenotyping, will increase their knowledge of how phenotyping data might complement the work of their own core facilities, and will acquire resources for future consultation, referral, and collaboration.