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Faculty: Leslie Citrome, MD, MPH Broadly defined as a state of extreme arousal characterized by excessive, poorly organized motor and/or verbal activity, agitation is a frequent cause of emergency psychiatric interventions and hospitalizations for patients with schizophrenia or bipolar disorder. In fact, studies suggest that as many as half of psychiatric emergency visits involve agitated patients. Differential diagnosis of the underlying cause can be challenging, particularly because patients often are uncooperative or otherwise unable to provide relevant details from their histories. In some cases, agitation can escalate to aggression and violent behavior, which can place the patient and members of the health care team at risk for injury. Thus, emergency care clinicians often are faced with the difficult tasks of quickly determining the etiology of agitation symptoms, implementing initial de-escalation efforts to decrease the likelihood of violent outbursts, and helping patients participate in assessment queries and treatment decisions. During this Interactive Exchange™ program, presenting faculty will discuss practical strategies for uncovering the likely cause of agitation, stratifying agitated patients with mental illnesses based on risks of aggressive behaviors, and implementing interpersonal and medical interventions that can ameliorate symptoms and reduce the utilization of seclusion and restraint. Additional resources are available here: http://www.exchangecme.com/agitation You can also visit http://www.ExchangeCME.com for access to additional video content as well as free CME activities in various therapeutic areas.