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Hybrid filler is a groundbreaking injectable formulation that marries synthetic calcium hydroxyapatite microspheres with a cross-linked hyaluronic acid. When hybrid filler is skillfully administered deep into the subcutaneous plane, the hyaluronic acid particles gracefully disperse among the collagen fibers of the lower dermal layer, instantly adding volume.Simultaneously, calcium hydroxyapatite microspheres embark on their journey through fibroblast activation, where they gradually deposit essential extra cellular matrix components, supporting the body’s natural collagen production and forming elastin and collagen fibers.Over time, this scaffold transforms into a strong collagen framework as the gel carrier degrades. This interplay of hyaluronic acid and calcium hydroxyapatite in hybrid filler delivers outstanding clinical outcomes. Dr. Nabil Fakih, the brainchild behind this groundbreaking idea, has extensively published research on its safety profile and its exceptional pro-lifting capacity. He made a pioneering contribution to the medical field by introducing and documenting the first one the term "hybrid filler" in the esteemed medical literature. Dr. Nabil Fakih exclusively utilizes and advocates for the use of the Radiesse and Belotero Hybrid Filler from Merz Aesthetics. His extensive research, alongside that of his colleagues, has demonstrated the impeccable safety and stability of this unique blend. Notably, his research about safety and pro-lifting in this area has been referenced in the following articles on PubMed: 1) Fakih-Gomez N, Kadouch J. "Combining Calcium Hydroxylapatite and Hyaluronic Acid Fillers for Aesthetic Indications: Efficacy of an Innovative Hybrid Filler." Aesthetic Plastic Surgery. February 2022;46(1):373-381. doi: 10.1007/s00266-021-02479-x. Epub 2021 Aug 2. PMID: 34341855; PMCID: PMC8831259. 2) Kadouch J, Fakih-Gomez N. "A Hybrid Filler: Combining Calcium Hydroxylapatite and Hyaluronic Acid Fillers for Aesthetic Indications." The American Journal of Cosmetic Surgery. 2022;39(3):182-189. doi: 10.1177/07488068211016135. Dr. Nabil Fakih www.drnabilfakih.com [email protected]