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Green fluorescent protein (GFP) is fantastic at helping scientists observe the inner workings of the cell. However, there are many disadvantages to using GFP; John Christie explains how his lab has developed new plant-derived fluorescent proteins which allow scientists to track viral infections more effectively. 0:00 Introduction 0:38 Understanding the inner-workings of cells 1:10 What is Green Fluorescent Protein (GFP)? 1:56 The disadvantages of using GFP 2:31 Using GFP to track infections 3:34 A new plant fluorescent protein to monitor viruses Speaker profile: John Christie obtain his degree in Biochemistry at the University of Glasgow going on to a PhD in Molecular Biology investigating how UV light regulates gene expression flavonoid biosynthesis. He is currently Professor of Photobiology and Deputy Head of the Institute of Molecular Cell and Systems Biology at the University of Glasgow. His research interests centre on using biophysical to physiological methods to understand how photosensory systems operate to shape plant growth and development. As well as identifying the long sought-after photoreceptor for phototropism and more recently the elusive plant UV-B photoreceptor, his work also extends to developing new optogenetic tools to non-invasively track bacterial and viral infections and control neural processes. Filmed on location at the Gatsy Plant Science Summer School, 2016.