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MPU Noon Seminar Series Speaker: Monica Serban, Ph.D., MCCPM Medical Physicist – Radiation Medicine Program & Clinician Investigator, Princess Margaret Cancer Centre Assistant Professor – Department of Radiation Oncology, University of Toronto Associate Member – Institute of Medicine Science, Toronto, Ontario Title: "Spatially Fractionated Radiotherapy, Clinical Implementation at Princess Margaret Cancer Centre" Abstract: This presentation will provide a comprehensive overview of the Spatially Fractionated Radiotherapy (SFRT) technique and its clinical implementation at Princess Margaret Cancer Centre. The presenter will discuss: • Overview of different SFRT implementations • Technique Development and Automation • Principles of Treatment Planning • Biological Considerations Behind SFRT • Overview of Patients Treated at PM and Early Outcomes • Dose Optimization and Treatment Delivery • Patient-Specific Quality Control Biographical Summary: Dr. Serban is a certified medical physicist and has worked at the Maisonneuve-Rosemont Hospital and McGill University Health Centre before she joined Princess Margaret Cancer Centre in February 2022. Her Ph.D. at Aarhus University, Denmark focused on gynecological brachytherapy. Dr. Serban is faculty and co-director of the ESTRO course on MRI-guided brachytherapy for gynaecological cancers. She has a longstanding expertise in RT technique development and clinical implementation. Her research interests lie in gyne brachytherapy outcomes optimization, dose accumulation, reirradiation and AI in the context of deformable registration.