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Download the "Solution Pharmacy" Mobile App to Get All Uploaded Notes, Model Question Papers, Answer Papers, Online Tests and other GPAT Materials - https://play.google.com/store/apps/de... The digestant is generally the main component of digestive fluid, such as dilute hydrochloric acid, amylase, pepsin, trypsin and the like. And the digestant is used for curing the weak secretion function of the digestive tract and acts as replacement therapy to quickly restore normal digestion activities. Some herbs, such as yeast, drug song, hawthorn, malt, and Gallus gallus domesticus, also contribute to digestion. There are some digestants which work by promoting the secretion of digestive juices, such as carnitine (vitamin BT), which can promote the secretion of digestive juices, and enhance the activity of digestive enzymes These are substances intended to promote the digestion of food. A number of proteolyses, amylolytic and lipolytic enzymes are marketed in combination formulations and are vigorously promoted for dyspeptic symptoms, and as appetite stimulants or health tonics. They are occasionally beneficial, only when their elaboration in g.i.t. is deficient. Their routine use of tonics and appetite-improving mixtures is irrational. 1. Dilute Hydrochloric Acid- It may be used in achlorhydria; 5–10 ml of dilute HCl (10%) should be further diluted to 100–200 ml with water and sipped with a straw (to prevent contact with teeth) during meals. 2. Pepsin- May be used along with HCl in gastric achylia due to atrophic gastritis, gastric carcinoma, pernicious anaemia, etc. 3. Papain- It is a proteolytic enzyme obtained from raw papaya. Its efficacy after oral ingestion is doubtful. 4. Pancreatin- It is a mixture of pancreatic enzymes obtained from hog and pig pancreas. It contains amylase, trypsin, and lipase; indicated in chronic pancreatitis and other exocrine pancreatic deficiency states. Fat and nitrogen content of stools may be reduced and diarrhoea/ steatorrhoea may be prevented. It has to be used as enteric-coated tablets or capsules to protect the enzymes from being themselves digested in the stomach by pepsin. Nausea, diarrhoea, and hyperuricemia are the occasional side effects 5. Diastase- These are amylolytic enzymes obtained from the fungus Aspergillus oryzae. They have been used in pancreatic insufficiency, but efficacy is equivocal. 6. Methyl Polysiloxane- (Dimethylpolysiloxane, Simethicone, Dimethicone) It is a silicone polymer, a viscous amphiphilic liquid—reduces surface tension and collapses froth, ‘antifoaming agent’. It is not absorbed from g.i.t. and is pharmacologically inert. Added to antacid, digestant and antireflux preparations (see above), it is claimed to relieve flatulence, to coat and protect ulcer surface, to aid dispersion of antacids in gastric contents, and to prevent gastroesophageal reflux. However, clinical efficacy is equivocal. Get in touch with the solution by just clicking following links- Facebook Group- / solutionpharamcy Facebook Page- / pharmavideo New channel (Pharmacy Dictionary) - / @pharmacydictionary Instagram- / solutionpharmacy E-Mail for official and other work - solutionpharmacy@gmail.com LinkedIn- / pushpendrakpatel #solutionpharmacy #Pharmacologyclass #GPATonlinetest