Introduction to Primary Tumor Growth and Neoangiogenesis скачать в хорошем качестве

Introduction to Primary Tumor Growth and Neoangiogenesis

Transcript: Welcome back to Understanding Cancer Metastasis. My name is Ken Valkenburg and I'm a post-doctoral research fellow in the Department of Urology at Johns Hopkins School of Medicine. I've been studying cancer for the past seven years and cancer metastasis for the last four. In this lecture, I will introduce the concepts of primary tumor growth and neoangiogenesis. At the end of this lecture, you will be able to: one, describe uncontrolled cell division as the defining property of cancer; two, define what a mutation is and describe its role in primary tumor formation; three, define neoangiogenesis and describe its role in primary tumor formation and metastasis; and four, describe a primary tumor microenvironment and list several other cell types present within a tumor. This lecture really covers the first steps of the metastatic process. Without a primary tumor, there is no metastasis. Understanding the formation of a tumor and the development of brand-new blood vessels that grow into a tumor helps us better understand how and why cancer cells leave where they are and travel to other parts of the body. video credit: ‪@coursera‬