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Watch the Manchester Neuroscience Seminar with Assistant Professor Ryota Tamura from Keio University School of Medicine. Ryota talks about translational research including anti-angiogenic immunotherapy for NF2-SWN tumours and stem cell based gene therapy using iPS cells for malignant glioma. Speaker Bio: Ryota Tamura specialises in neurosurgical and translational approaches to brain tumours, with a focus on refractory benign tumours such as NF2-related schwannomatosis and malignant glioma. He is particularly skilled in skull base techniques for posterior cranial fossa tumours. His research includes anti-angiogenic immunotherapy for unresectable benign tumours. He led the first immunotherapeutic trial for NF2-related schwannomatosis using a VEGF receptor peptide vaccine, which showed promising results. A randomised placebo-controlled study is planned for 2025. Ryota also leads preclinical studies on stem cell-based gene therapy using genome-edited iPS cells for malignant glioma. A clinical trial using iPS cell-derived neural stem cells is scheduled for 2026. These innovative strategies aim to improve outcomes for patients with challenging brain tumours. This seminar was hosted by Professor Omar Pathmanaban.