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Bird Flu H5N1 (HPAI) Virus has been continuing to evolve with more human cases and a growing concern from the larger infectious disease community about new human cases. In this video, we dive into new mutations found in a teenager infected with Bird Flu and what it may mean for the risk of an outbreak in the future. Introduction: 0:00 - 2:02 Overview: 2:02 - 7:29 (origin of Bird Flu, historic cases, spread into cattle, human cases, viral presence in milk, population seropositivity, and more) 7:30 - 10:20: Canadian teenager without previous exposure critically ill with Bird Flu 10:21 - 14:35: Canadian teenager found to have viral mutation PB2 E627K and also found in one other Texas man 14:36 - 17:38: What is PB2 in Bird Flu viruses? 17:39 - 22:26: PB2 E627K has evolved in past in a human infected with Bird Flu 22:27 - 24:24: PB2 E627K present in 70% of cases in previous Chinese outbreak that had ~40% mortality and responsible for increased replication, pathogenicity, and spread 24:25 - 27:34: PB2 mutations may help virus infect human lung epithelial cells Playlist on Bird Flu: • Bird Flu H5N1 Please scroll below to see resources and studies used! PREVIOUS BIRD FLU VIDEOS! Bird Flu H5N1 - Overview and New Concerning Mutations • Bird Flu H5N1 - Overview and New Conc... Bird Flu Outbreak - Human to Human Spread • Bird Flu Outbreak - Human to Human Sp... Bird Flu Update #4 - Another Human Case, New Symptoms, Domestic Cats Infected, Testing Dairy Supply • Bird Flu H5N1 - Another Human Case, N... Bird Flu Update #3 - Second Human Case of H5N1 Detected in Michigan Man From Infected Cow • Bird Flu H5N1 - Second Human Case of ... Bird Flu (H5N1) Update #2 - History, Cattle Spread, Milk, Beef, Wastewater Surveillance, Human Risk • Bird Flu H5N1- History, Cattle Sprea... Bird Flu (Avian) H5N1 - Should We Be Concerned - Full Review (Origin, Spread, Human Cases, Symptoms) • Bird Flu (Avian) H5N1 - Should We Be ... Bird Flu Update After Death Of Young Girl AND Omicron Update - Cases, Hospitalizations, Variants • Bird Flu Update After Death Of Young ... Sources: https://journals.asm.org/doi/10.1128/... https://pmc.ncbi.nlm.nih.gov/articles... https://pmc.ncbi.nlm.nih.gov/articles... https://gisaid.org/resources/gisaid-i... 👇DON'T MISS OUT - JOIN OUR PATREON COMMUNITY TODAY 👇 / whiteboardmedicine We appreciate the support! COLLECTION OF PLAYLISTS: Critical Care Medicine 🚑 • Critical Care Pulmonology🫁 • Pulmonology Cardiology and ECG🫀 • Cardiology Nephrology🧂 • Nephrology Acid Base🧬 • Acid-Base Disorders Medical, Healthcare, and Science News📰 • Medical, Healthcare, And Science News Biostatistics and Research📊 • Biostatistics and Research Design Immunology🧫 • Immunology Laboratory Evaluation and Values🧪 • Laboratory Values Infectious Disease🦠 • Infectious Disease Endocrinology🎂 • Endocrinology ________________________________________________________________________ If you enjoy the content and feel inclined, here are some ways in which you can support us! PayPal: https://www.paypal.com/donate?hosted_... YouTube Membership tab: It has a “Join” button at the top right corner of our Channel’s home page. We appreciate you! DISCLAIMER THIS VIDEO DOES NOT PROVIDE MEDICAL ADVICE. The information, including but not limited to, text, graphics, images and other material contained on this website are for informational purposes only. No material on this site is intended to be a substitute for professional medical advice, diagnosis or treatment. Always seek the advice of your physician or other qualified health care provider with any questions you may have regarding a medical condition or treatment and before undertaking a new health care regimen, and never disregard professional medical advice or delay in seeking it because of something you have read, watched, or listened to on this video, or any other videos, reports, texts tweets or other sources. #birdflu #avianflu #h5n1 #pandemic #outbreak #birdflunews #medicaleducation