Identification: Kinesin-1 Cargos Using Fluorescence Microscopy l Protocol Preview скачать в хорошем качестве

Identification: Kinesin-1 Cargos Using Fluorescence Microscopy l Protocol Preview

Watch the Full Video at https://www.jove.com/v/53632/identifi.... Identification of Kinesin-1 Cargos Using Fluorescence Microscopy - a 2 minute Preview of the Experimental Protocol Clement M. Lee Icahn School of Medicine at Mount Sinai, Department of Oncological Sciences; Here, a protocol is presented to identify Kinesin-1 cargos. A motorless mutant of the Kinesin-1 heavy chain (KIF5B) aggregates in the cytoplasm and induces aggregation of its cargos. Both aggregates are detected under fluorescence microscopy. A similar strategy can be employed to identify cargos of other motor proteins. Visit https://www.jove.com?utm_source=youtu... to explore our entire library of 14,000+ videos of laboratory methods and science concepts. JoVE is the world-leading producer and provider of science videos with the mission to improve scientific research and education. Millions of scientists, educators, and students at 1500+ institutions worldwide, including schools like Harvard, MIT and Stanford benefit from using JoVE's extensive library of 14,000+ videos in their research,education and teaching. Subscribe to our channel:    / jovejournalofvisualizedexperiments