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In 1967, the fight against malaria was being lost. Chloroquine was failing as the parasite developed resistance. In hospitals across Africa and Asia, the disease claimed nearly one million lives in a single year. Professor Tu Youyou was recruited to a top-secret military project named Project 523. While her contemporaries focused on modern chemistry, she turned to texts written over 1600 years ago. Her team tested over 2000 traditional remedies and created 380 herbal extracts, testing each with rigorous determination. The breakthrough came from a text called A Handbook of Prescriptions for Emergencies. Following a simple recipe from a fourth-century physician, the team isolated a compound that showed 100% effectiveness. To ensure it was safe for the world, Professor Tu and her team became the first human subjects to test the drug on themselves. Artemisinin-based therapies are now the global standard for treatment. The result is a dramatic drop in malarial deaths worldwide, saving millions of lives. For decades, the discovery spread quietly while the researcher remained in relative obscurity. Official recognition eventually followed, but the work was never about the accolade. This film is a tribute to Professor Tu Youyou on her 95th birthday, December 30th. Her work continues to save lives. The greatest impacts often begin with the quiet determination of one person. Sources & Further Reading 1. Nobel Prize – Tu Youyou: Biographical https://www.nobelprize.org/prizes/med... 2. Miller, L. H., & Su, X. (2011). Artemisinin: Discovery from the Chinese Herbal Garden. Cell https://doi.org/10.1016/j.cell.2011.0... 3. Su, X., & Miller, L. H. (2015). The discovery of artemisinin and Nobel Prize in Physiology or Medicine. Science China Life Sciences https://doi.org/10.1007/s11427-015-49... 4. Lasker Foundation – Artemisinin Therapy for Malaria https://laskerfoundation.org/winners/... 5. Valavanidis, A. (2019). Discovery of Antimalarial Drug Artemisinin https://www.researchgate.net/publicat... Image Credits By Bengt Nyman from Vaxholm, Sweden - 810_4987 Tu Youyou, medicine, CC BY 2.0, https://commons.wikimedia.org/w/index... By Xinhua News agency - http://www.chinadaily.com.cn/micro-re..., Public Domain, https://commons.wikimedia.org/w/index...