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Watch the Full Video at https://www.jove.com/v/52611/trabecul.... Trabecular Meshwork Response to Pressure Elevation in the Living Human Eye - a 2 minute Preview of the Experimental Protocol Larry Kagemann, Bo Wang, Gadi Wollstein, Hiroshi Ishikawa, Brandon Mentley, Ian Sigal, Richard A Bilonick, Joel S Schuman University of Pittsburgh School of Medicine, Department of Ophthalmology, UPMC Eye Center, Eye and Ear Institute, Ophthalmology and Visual Science Research Center; University of Pittsburgh, Department of Bioengineering, Swanson School of Engineering; University of Pittsburgh School of Medicine, The McGowan Institute for Regenerative Medicine; University of Pittsburgh, Deptartment of Biostatistics, Graduate School of Public Health; Trabecular meshwork (TM) migration into Schlemm’s canal space can be induced by acute pressure elevation by ophthalmodynamometer, and observed by spectral domain optical coherence tomography. The goal of this method is to quantify the morphometric response of the living outflow tract to acute pressure elevation in living tissues in situ. Visit https://www.jove.com?utm_source=youtu... to explore our entire library of 14,000+ videos of laboratory methods and science concepts. JoVE is the world-leading producer and provider of science videos with the mission to improve scientific research and education. Millions of scientists, educators, and students at 1500+ institutions worldwide, including schools like Harvard, MIT and Stanford benefit from using JoVE's extensive library of 14,000+ videos in their research,education and teaching. Subscribe to our channel: / jovejournalofvisualizedexperiments