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Kadian is a medication used to help relieve severe ongoing pain, such as pain due to cancer. It belongs to a class of drugs known as opioid analgesics and works in the brain to change how your body feels and responds to pain. It is important to note that the higher strengths of this drug (100 milligrams per capsule and higher) should only be used if you have been regularly taking moderate to large amounts of an opioid pain medication. Using these higher strengths without a tolerance to opioids can cause overdose, and even death. It is also important to remember that Kadian should not be used for mild or short-term pain relief. This medication is not for occasional ("as needed") use. Always follow your doctor's instructions and take the prescribed dosage at the recommended times for the best results. f51d