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Cervical cancer SLNB lymphadenectomy disease-free survival surgical complications early-stage cervical cancer clinical trial PHENIX study sentinel lymph node biopsy. Dive into the latest findings from the PHENIX trial published in The New England Journal of Medicine. This phase III study compared sentinel lymph node biopsy (SLNB) alone versus full lymphadenectomy in women with early-stage cervical cancer. Key results show SLNB was noninferior in disease-free survival at 3 years, with fewer complications like lymphocyst, lymphedema, paresthesia, and pain. Learn about the study details: 838 patients enrolled from 2015 to 2023, with median follow-up of 62.8 months. Disease-free survival was 96.9% in the biopsy-only group versus 94.6% in the lymphadenectomy group. Cervical cancer-specific survival favored the biopsy-only approach, and no retroperitoneal nodal recurrences occurred in that group. Understand why this could change standard care for early-stage cervical cancer by reducing surgical risks while maintaining efficacy. Perfect for oncologists, patients, and anyone interested in cancer research advancements.