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In last week’s issue of The Cancer Letter, Jacquelyn Cobb, associate editor, wrote a story about the then-promising legislative package that was passed by the U.S. House of Representatives Jan. 22. At the time, the package was expected to pass in the Senate, provide funding for the federal government through fiscal year 2026, and prevent a government shutdown that looms Jan. 30. Then, on Jan. 24, 37-year-old ICU nurse Alex Pretti was shot in Minneapolis while trying to document the actions of U.S. Immigration and Customs Enforcement agents. In this week’s episode of The Cancer Letter Podcast, Jacquelyn and Paul Goldberg, editor and publisher of The Cancer Letter, talk about how the future of the House-FY26 spending package—and its implications for NIH and NCI funding, as well as pediatric cancer initiatives and other important healthcare stipulations—has dissolved as lawmakers refuse to move forward a spending bill without changes to ICE and the Department of Homeland Security. “There we were, staying in our lane covering nothing but the stuff we cover, which is oncology,” Paul, editor and publisher of The Cancer Letter, said. “So, suddenly, a 38-year-old nurse from the VA gets killed while trying to document what ICE is doing in Minneapolis. “And suddenly the bill, the spending bill, which includes the Department of Homeland Security spending, is derailed. So, we are trying to stay within our lane and cover only oncology and then the world catches up, which also kind of tells you that there are no safe places anymore,” Paul said. The events of the last week reminded Paul that “staying in our lane” is not always possible. “I'm seeing one thing only,” Paul said. “There is no safe harbor that I thought we were kind of seeking so we could focus only on our stuff because The New York Times does a very nice job of covering the rest of the administration. We cover our part of the administration. Well, now we are seeing that our part of administration is becoming more like ‘Well, there's no safe harbor. It's very hard to delineate.’” Stories mentioned in this podcast include: Premarin's 84-year hold on the market ends as FDA approves a generic version Spending bill passed by the House gives NIH $415M raise, NCI gets $128M Legislation caps proportion of NIH grants to receive multiyear funding; indirect costs remain untouched Fifth time’s a charm? Mikaela Naylon Give Kids a Chance Act is included in FY26 spending bill Blood Cancer United: A new name at the right moment NIH ends fetal tissue research—again A transcript of this podcast is available: https://cancerletter.com/podcastc/202...