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In this episode, neurologist and stroke expert Dr. Robert D. Brown discusses the critical role of genetics in assessing unruptured intracranial aneurysm risk. He highlights emerging technologies for detection and management, emphasizing personalized surveillance strategies and non-invasive imaging technologies. Dr. Brown stresses the importance of patient education and lifestyle modifications in risk mitigation. The episode concludes by exploring future research directions and the need for multidisciplinary collaborations to advance treatment options. Note: This lecture was recorded in May 2023. Learn more about Dr. Robert D. Brown’s work: https://www.mayoclinic.org/biographie... Learn more about Dr. David Dodick: https://www.atria.org/doctors/dr-davi... Time stamps: 00:00:16: Intro 00:05:01: Dr. Robert Brown 00:08:37: Medical disorders associated with aneurysms 00:12:51: Implications of aneurysm detection and treatment options 00:14:05: Advanced treatments for aneurysms 00:16:52: Screening recommendations for familial aneurysmal cases 00:21:59: The impact of hypertension and smoking on aneurysm detection 00:25:52: Epidemiology and risk factors of subarachnoid hemorrhage 00:33:20: Impact of family history on aneurysm rupture rate 00:34:42: Morbidity and mortality associated with aneurysm clipping and coiling 00:37:37: Considerations for conservative treatment of unruptured intracranial aneurysm 00:41:41: The Unruptured Intracranial Aneurysm Treatment Score (UIATs) 00:48:00: Predictive score for aneurysm growth 00:50:55: Recommendations for repeat imaging 00:54:28: Treatment and management options 01:00:01: Dilemmas in unruptured aneurysms management 01:02:31: Challenges in clinical trials 01:03:00: Unresolved clinical questions 01:04:25: Strategies to lower rupture risk 01:05:52: Closing remarks — About: Atria’s Vanguard Symposia is a lecture series where some of the world’s most compelling researchers translate leading-edge science into medicine. In each episode, top experts share breakthrough science about preventive health care, dive deep into headline-grabbing topics, and take you beyond the buzzwords to explain the latest in longevity science. Our show will arm you with practical information and the tools of discernment to cut through the hype and understand what matters most. Atria Health and Research Institute aims to accelerate a global shift from reactive sick care to proactive, preventive health care. We work at the forefront of science and technology and we believe a collaborative approach to modern medicine can extend healthy life for all. Learn more: https://www.atria.org/ Subscribe to Atria’s Vanguard Symposia on: Apple Podcasts: https://bit.ly/AtriaVanguardApplePodc... Spotify: https://bit.ly/AtriaVanguardSpotify Sign up for our newsletter: https://bit.ly/Atria-Newsletter The information contained in this podcast is for general informational and educational purposes only and does not constitute or serve as a substitute for professional medical advice, treatment, or diagnosis. Always consult the advice of your personal health care provider when seeking medical advice for any condition you may have, and never delay treatment or disregard advice from a professional health care provider based on something you have seen or heard in this content. No part of this podcast can be reproduced, redistributed, published, copied or duplicated in any form without the prior written permission of Atria.