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Great white sharks (Carcharodon carcharias) have a genetic mystery that defies evolutionary logic: their nuclear DNA is nearly identical across the globe, but their mitochondrial DNA shows dramatic differences — especially between South Africa and other populations. For over two decades, scientists believed female philopatry (returning to breeding grounds) explained this "mito-nuclear discordance." But a new study in PNAS with the largest genetic dataset ever assembled has ruled out this long-standing theory — along with genetic drift and reproductive skew. The only remaining possibility? An extremely powerful form of natural selection — so strong it would eliminate any shark with "wrong" mitochondrial DNA. But even that seems unlikely given their small global population (~20,000). So for now… science has no answer. 🔍 Source: Florida Museum of Natural History / PNAS (2025) DOI: 10.1073/pnas.2507931122 #GreatWhiteShark #DNA #ScienceMystery #Evolution #MarineBiology #Sharks #Genetics #Wildlife #OceanLife #ScienceFacts #DidYouKnow #AnimalFacts #YouTubeShorts #ScienceTok #Biology #NatureIsWeird