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Welcome to Chemiverse By SK, In this video we'll discuss the Synthesis of Pyrrole with different methods. Pyrrole synthesis encompasses several methods, each with its own unique approach. Here's a concise overview of the most common methods: Paal-Knorr Synthesis: Involves the reaction of a 1,4-dicarbonyl compound (e.g., diethyl succinate) with a primary amine (e.g., ammonia) under acidic conditions to yield pyrrole. Knorr Synthesis: Similar to Paal-Knorr but uses a 1,3-diketone or a 1,3-dialdehyde as the starting material. The reaction with ammonia or a primary amine forms pyrrole. Trofimov Synthesis: Utilizes α-aminoketones as starting materials, which undergo cyclization in the presence of acid to yield pyrroles. Piloty-Robinson Synthesis: Involves the condensation of an α-amino ketone with a β-keto ester in the presence of acid, followed by decarboxylation and cyclization to form pyrrole. Van Leusen Synthesis: In this method, an α-diazo ketone undergoes a 1,5-electrocyclization to yield pyrrole. Barton-Zard Synthesis: Involves the reaction of a 1,4-diketone with a sulfonylhydrazone and a reducing agent, leading to a radical cascade reaction that forms pyrrole. Chapters 0:00 Introduction to Pyrrole 1:46 Paal-Knorr Synthesis 9:34 Knorr Synthesis 23:53 Trofimov synthesis 30:40 Piloty Robinson synthesis 36:48 Van Leusen synthesis 41:45 Barton Zard synthesis Other lectures Hoffmann degradation • Hoffmann Bromamide Degradation Reaction wi... Curtius Rearrangement • Curtius Rearrangement In Easy Steps with R... Schmidt & Lossen rearrangement • Schmidt and Lossen Rearrangements With Eas... Beckman rearrangement • Beckmann Rearrangement | Caprolactum Synth... Molecular rearrangement Playlist • molecular rearrangements Quieres Pyrrole synthesis? Organic synthesis? Paal knorr synthesis? Knorr synthesis? Trofimov synthesis? Piloty Robinson synthesis? Van leusen synthesis? Barton zard synthesis? Heterocyclic compounds synthesis? Book Name Heterocyclic Chemistry By J.A Joule & K. Mills 5th edition #Pyrrolesynthesis #paalknorrsynthesis #knorrsynthesis #trofimovsynthesis #pilotyrobinsonsynthesis #vanleusensynthesis #bartonzardsynthesis #heterochemistrybyjoules&mill #organicsynthesis Thanks for watching!