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Watch the Full Video at https://www.jove.com/v/52019/experime.... Experimental and Imaging Techniques for Examining Fibrin Clot Structures in Normal and Diseased States - a 2 minute Preview of the Experimental Protocol Natalie K. Fan, Philip M. Keegan, Manu O. Platt, Rodney D. Averett Georgia Institute of Technology & Emory University School of Medicine, Wallace H. Coulter Department of Biomedical Engineering; Georgia Institute of Technology, Parker H. Petit Institute for Bioengineering & Bioscience; Georgia Institute of Technology, George W. Woodruff School of Mechanical Engineering; In this manuscript, experimental techniques, including blood preparation, confocal microscopy, and lysis rate analysis, to examine the morphological differences between normal and abnormal clot structures due to diseased states are presented. Visit https://www.jove.com?utm_source=youtu... to explore our entire library of 14,000+ videos of laboratory methods and science concepts. JoVE is the world-leading producer and provider of science videos with the mission to improve scientific research and education. Millions of scientists, educators, and students at 1500+ institutions worldwide, including schools like Harvard, MIT and Stanford benefit from using JoVE's extensive library of 14,000+ videos in their research,education and teaching. Subscribe to our channel: / jovejournalofvisualizedexperiments