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Dr. Nancy Klimas, a pioneering doctor and researcher in ME/CFS and long COVID, recently appeared on the Make Visible Podcast to talk about what she’s learned from decades of working with people who live with complex, often misunderstood illnesses. Dr. Klimas explains how these conditions can throw the body out of balance and why so many people remain sick for years without clear answers. Instead of chasing symptoms, she believes in treating the whole person, looking at how hormones, the immune system, and even gender can shape the way someone experiences illness and healing. She also shares details about an exciting new clinical trial using monoclonal antibodies to remove leftover spike protein from the body, which may be driving long COVID symptoms for many. For anyone living with ME/CFS, long COVID, or another invisible illness, this episode is a reminder that progress is being made and you’re not alone. Key points: 00:01 Introduction 03:16 Bridging science, clinic, and patient voices. 05:19 How computational modeling accelerated research. 07:19 Launching the monoclonal antibody study. 09:00 Spike protein as a long COVID driver. 12:17 How the AstraZeneca drug helps remove spike protein. 15:24 State and private funding for the study. 18:19 Why cautious optimism is important. 19:38 The RECOVER initiative and long COVID science. 23:06 Why sex differences matter in chronic illness. 25:40 Hormones, inflammation, and modeling illness 27:50 Integrative medicine vs. fragmented care. 30:24 The layered approach to treating complex illness. 33:28 How lifestyle adaptation supports healing. 35:47 Cultural differences in chronic illness treatment. 39:03 Using AI and big data to reveal new insights. 43:07 Comparing long COVID with ME/CFS cohorts. 49:32 Ongoing studies: rebooting systems and microbiome work 50:12 Food, nutrients, and sleep as therapy for chronic illnesses. Nancy Klimas, M.D., is the Director of the Institute for Neuro-Immune Medicine where she directs a group of remarkable interdisciplinary scientists and clinicians. They collaborate to discover innovative strategies for treating and preventing chronic illnesses, while also focusing on training the next generation of clinicians and scientists. With 40 years of professional experience, Dr. Nancy Klimas is internationally recognized for her work in multi-symptom disorders, including ME/CFS, GWI, fibromyalgia, and Long COVID. LinkedIn: / nancy-klimas-49255178 Instagram: / nancyklimas X: https://x.com/ngklimas Follow the Make Visible Podcast. YouTube: / @makevisiblepodcast PodLink: https://pod.link/1767819213 Apple Podcasts: https://podcasts.apple.com/us/podcast... Spotify: https://open.spotify.com/show/7D3qAhd... Instagram: / visible.health Learn more about the Institute for Neuroimmune Medicine here. Website: https://www.nova.edu/nim/ Facebook: / instituteforneuroimmunemedicine Instagram: / nsu_inim Twitter: / nsu_inim #LongCOVIDResearch #ChronicIllnessSupport #MonoclonalAntibodies