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Dapagliflozin (brand name Forxiga) is a Sodium-glucose co-transporter 2 (SGLT2) inhibitor and is prescribed for adults with type 2 diabetes mellitus to improve their diabetic control when diet and exercise alone are not enough for good control. It can also be used to treat heart failure and chronic kidney disease (CKD). This video will explain everything you needs to know about SGLT2 inhibitors, including common and uncommon side-effects such as Thrush, Fourniers Gangrene and Diabetic Ketoacidosis (DKA). We will also give you advice about how to manage some of the side-effects. • GLUCOPHAGE SHOCKING SIDE-EFFECTS, SECRETS ... • RYBELSUS: UNCOVERING THE TRUTH ABOUT SIDE-... • THE TRUTH ABOUT SIDE-EFFECTS: PANCREATIC C... In Diabetes, SGLT2 inhibitors are given on their own in patients for whom the use of metformin is considered inappropriate due to reasons of intolerance or contraindications. SGLT2 inhibitors can also be given with other glucose-lowering drugs, including insulin, when these drugs do not provide adequate diabetic control. The SGLT2 inhibitor-containing medicines marketed in the UK are Forxiga▼ (dapagliflozin), Xigduo▼ (dapagliflozin and metformin), Jardiance▼ (empagliflozin), and Synjardy▼ (empagliflozin and metformin) Edistride ▼(dapagliflozin), Ebymect ▼(dapagliflozin/metformin), Qtern ▼(dapagliflozin/ saxagliptin), Invokana▼ (canagliflozin), Vokanamet▼ (canagliflozin/metformin), Glyxambi▼ (empagliflozin/linagliptin), Steglatro▼ (ertugliflozin), Segluromet▼ (ertugliflozin/metformin), and Steglujan▼ (ertugliflozin/sitagliptin) #dapagliflozin #sglt2inhibitors #type2diabetes Timeline: 00:00 Introduction 01:03 What is Dapagliflozin? 02:16 How do you take it? 02:51 What are the common side-effects? 06:11 What are the uncommon side-effects? 09:10 What are the cautions with other medicines? 10:39 Do you stop taking SGLT2 inhibitors if you become unwell? 11:19 What is the 'Sick Day Guidance'? Clinical data: UK Drug Safety update on SGLT2 inhibitors and reports of Fournier’s gangrene: https://www.gov.uk/drug-safety-update... and the FDA Safety announcement: https://www.fda.gov/drugs/drug-safety... UK Drug Safety update about SGLT2 inhibitors and Risk of Diabetic Ketoacidosis https://www.gov.uk/drug-safety-update... UK Drug Safety Update on SGLT2 inhibitors and increased Risk of Lower-limb Amputation (mainly toes): https://www.gov.uk/drug-safety-update... Disclaimer: The videos posted will be for general informational purposes only. They should not be used to self-diagnose or a substitute for a medical exam, cure, treatment, diagnosis, prescription, or recommendation. You should not make any changes to your health regimen or diet before first consulting a doctor.