Human Amniotic Membrane (h-AM) subretinal implant скачать в хорошем качестве

Human Amniotic Membrane (h-AM) subretinal implant

Surgical repair of a refractory full thickness macular hole (FTMH) of 800 microns in diameter using a h-AM subretinal implant. We first performed phacoemulsification with IOL implant, then we enlarged the previous ILM peeling and also induced the detachment of neuroepithelium around the edge of the macular hole using a passive aspiration needle 27G soft-tip. The surgical maneuvers were performed bimanually under twinlight chandelier. A h-AM patch of 1mm in diameter was harvested and brought into the vitreous cavity using ILM forceps through a trocar, which valve had just been removed. The h-AM patch was implanted under the retinal edges of the FTMH with the stromal layer facing the retinal pigment epithelium (RPE) and then fluid/air exchange was performed. The aim of this procedure is to favor the interaction between hAM and retinal structures – RPE. There are few published data in the literature: Rizzo el (Retina 2018, Acta 2019) published h-AM implant for FTMH with MH closure with fully stratified neuroretina and without postop inflammation. h-AM has been also reported for repairing choroidal damage and patching retinal breaks. (Zhu D et al Acta Ophth 2017; Harutta M Eye 2017). The near prospective is to place the h-AM on the retina instead under the retina, in order to get the retinal break closed (because the h-AM seems to don't have any regeneration activity if placed under the retina).