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Peptic ulcer disease (PUD) is a medical condition in which ulcers are formed in the inner stomach lining, the first part of the small intestine (duodenum), and rarely the lower esophagus as well. The stomach lining is protected by the mucus layer, but various factors lead to the reduction in this protective layer which leads to ulceration. These ulcers include stress and refractory ulcers. ▬ 📌 Peptic Ulcer Etiology This section started with a mention of the epidemiology of peptic ulcer disease. Amongst the various causes, HP infection, aspirin, and NSAIDs alongside idiopathic ulcers are a few. Two types of ulcers are discussed here which include the refractory and stress ulcers. ▬ 📌 Peptic Ulcer Management Peptic ulcer presents with a range of clinical and alarm features. The latter includes left supraclavicular lymphadenopathy, palpable abdominal mass, and dysphagia. Diagnosis can be done via EGD, endoscopy (expensive), and gastric mucosal biopsies. Moreover, medical therapy (using antacids) along with anti-secretory agents (H2RAs and PPIs) are used. Additionally, mucosal protective agents are also taken. ▬ 📌 PUD Complications Prevention of the condition involves the use of antacids, H2RAs, and misoprostol. Furthermore, PPIs and COX-2 inhibitors can be taken. Bleeding can be treated via endoscopic therapy, injection methods, and angiographic therapy. However, perforation can be treated through medical therapy and laparoscopic repair. Whereas, obstruction is treated using endoscopic balloon dilation and truncal vagotomy or antrectomy. ▬ 🎬 5500+ sqadia.com Medical Videos ▬▬▬▬▬▬▬▬▬▬ 👩🏻⚕️ Accessible Medical Student Education 24/7/365 💡 Simplifying Medical Learning 💪 Study Hard, Dream Big, Achieve More