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Are you struggling with anxiety, hormone issues, sleep problems or trouble losing weight — and wondering if your genes could be playing a role? In this video, I break down what happens when you have a slow COMT enzyme AND a slow MTHFR gene variant. You’ll learn: -The role of MTHFR in recycling methyl groups and supporting detox -How COMT uses those methyl groups to clear neurotransmitters and hormones -What happens when BOTH are slow — and why that can leave you anxious, wired, or completely burned out -Practical nutrition and lifestyle tips to better support methylation and detox I’ll also share why supporting your methylation cycle (MTHFR) and enzyme activity (COMT) together is the key to restoring balance, energy, and calm. Want to go deeper support with MTHFR, no gallbladder or MTHFR? GET MORE SUPPORT 👉🏻Join Metabolism Tune-up: https://health-and-healing-with-lisa.... FACEBOOK: / lisahealthjoy INSTAGRAM: / lisahealthjoy TIKTOK: https://tiktok.com/lisahealthjoy MTHFR explained COMT explained slow COMT symptoms slow MTHFR symptoms MTHFR and COMT together Methylation explained Methylation cycle support What is MTHFR What is COMT enzyme Genetic mutations MTHFR COMT MTHFR anxiety fatigue COMT dopamine estrogen MTHFR metabolism weight loss liver methylation detox support