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Diving into the Fibers of the Brain

In this video we take a closer look at the white matter in the brain as captured with diffusion tensor imaging (DTI). We start with a sagittal view (left side of the brain), and a T1 anatomical image slides from left to right through the fiber tracts of the brain. Then the brain rotates to provide us a view at the front of the brain (coronal view), as if facing the individual. Next the image zooms in and provides a closer look at the corpus callosum (the fibers that cross from left to right in red), a fiber pathway essential for our hemispheres to communicate. The brain rotates further and we focus on the green fibers that cross over the corpus callosum, the fibers of the cingulum bundle, limbic fibers important for executive function, pain and emotion. We see both the left and the right sides. As the brain continues its rotation we find ourselves in a forest of fibers that project upwards toward the cortex. These are the fibers of the corona radiata, important for sensory and motor systems. Next we zoom out and take a look at the lower aspects of the brain, and come across the corticospinal tract. The corticospinal tract, in purple, has taken the fibers from the corona radiata and has collected and organized them to course towards the spinal cord as they are carrying sensory and motor signals. You will now also notice the red fibers that run perpendicular to the corticospinal tract. These fibers are part of the pons. This structure connects forebrain to cerebellar regions and is important for sleep, breathing and other involuntary actions. As we move back up we can spot the blue fibers that wrap around the thalamus underneath the corpus callosum, these are the fibers of the fornix. The fornix connects the hippocampus to other limbic structures, and is important for emotion and memory. Finally we zoom out and spot the uncinate fasciculus. These fibers are c-shaped and connect the temporal lobes to the prefrontal lobes, and are important for emotion regulation and anxiety. Here ends our dive into the brain. If you enjoyed this video and would like to learn more, come on over to diffusion-imaging.com, where you can learn more about the technologies and processing steps that create these images. http://diffusion-imaging.com