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Official Ninja Nerd Website: ninjanerd.org Ninja Nerds! In this endocrine physiology lecture, Professor Zach Murphy presents a detailed overview of Oxytocin, a hormone synthesized in the hypothalamus and secreted by the posterior pituitary. This lecture explores oxytocin’s crucial roles in reproductive physiology and neuroendocrine regulation. We begin by tracing oxytocin’s origin from the paraventricular nucleus of the hypothalamus and its transport via the hypothalamo-hypophyseal tract into the bloodstream. The lecture focuses on its primary physiologic actions, including uterine smooth muscle contraction during labor and the milk let-down reflex during breastfeeding, both mediated by positive feedback loops that amplify oxytocin release in response to sensory stimuli. We also examine oxytocin’s receptor signaling via Gq-protein coupled receptors, leading to intracellular calcium mobilization and smooth muscle contraction. Additional discussion includes its emerging roles in social bonding, emotional regulation, and potential therapeutic applications in psychiatric and obstetric care. Enjoy the lecture and support us below! 🌐 Official Links Website: ninjanerd.org Podcast: podcast.ninjanerd.org Store: merch.ninjanerd.org 📱 Social Media / ninjanerdlectures / ninjanerdlectures / ninjanerdlectures x.com/ninjanerdsci/ / ninja-nerd 💬 Join Our Community Discord: / discord #ninjanerd #Oxytocin #Endocrinology