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Definition and Differentiation: Tingling: Pins and needles sensation, often described as prickling or light electrical shocks. Numbness: Loss of sensation, including touch, pain, or temperature. It suggests more severe nerve damage compared to tingling. Most Common Cause - Transient Paresthesia: Caused by temporary nerve compression (e.g., sitting cross-legged or sleeping on an arm). Resolves upon changing position and is a universal experience. Diabetic Neuropathy: Affects about 50 percent of diabetic patients, especially with poor glucose control (blood sugar 180 milligrams per deciliter). Symptoms start as tingling and burning in a "stocking-glove pattern" (toes and fingers progressing upward). Carpal Tunnel Syndrome: Results from compression of the median nerve in the wrist. Symptoms include tingling in the thumb, index, and middle fingers, often worsening at night. Common in repetitive hand movements. Vitamin B12 Deficiency: Tingling and numbness are early signs due to nerve damage. Common in vegetarians, older adults, and chronic alcohol users. Treated with B12 supplements or injections. Alcoholic Neuropathy: Chronic alcohol use directly damages nerves and causes B vitamin deficiencies. Initial symptoms are tingling in the feet, progressing to numbness, muscle weakness, and balance issues. Radiculopathy: Nerve root compression or irritation caused by disc herniation or spinal stenosis. Symptoms include radiating tingling or numbness down arms or legs, often with shooting pain (e.g., sciatica). Multiple Sclerosis (MS): An autoimmune disease damaging the nerve's protective covering (myelin). Causes variable patterns of tingling and numbness, depending on the nerves affected. Hallmark Symptoms: Each condition has hallmark signs, such as the stocking-glove pattern in diabetic neuropathy or thumb and finger tingling in carpal tunnel syndrome. Management: Early treatment and lifestyle changes (e.g., diabetes control, adequate B12 intake) can prevent progression. Medications like pregabalin, gabapentin, or corticosteroids may relieve symptoms but do not reverse nerve damage in most cases. By BruceBlaus. When using this image in external sources it can be cited as:Blausen.com staff (2014). "Medical gallery of Blausen Medical 2014". WikiJournal of Medicine 1 (2). DOI:10.15347/wjm/2014.010. ISSN 2002-4436. - Own work, CC BY 3.0, https://commons.wikimedia.org/w/index... By BruceBlaus. When using this image in external sources it can be cited as:Blausen.com staff (2014). "Medical gallery of Blausen Medical 2014". WikiJournal of Medicine 1 (2). DOI:10.15347/wjm/2014.010. ISSN 2002-4436. - Own work, CC BY 3.0, https://commons.wikimedia.org/w/index... By Manu5 - Top Medical Animation Studio, CC BY-SA 4.0, https://commons.wikimedia.org/w/index... Disclaimer: This information is provided for general knowledge and educational purposes only. It is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always consult with your doctor for any questions or concerns you may have about your health.