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#anandamide #medicalmarijuanapatient #mentalhealth #thepittsburghpodcast Anandamide, also known as N-arachidonoyl ethanolamine (AEA), is a fatty acid neurotransmitter¹. It was the first endocannabinoid to be discovered and participates in the body's endocannabinoid system by binding to cannabinoid receptors¹. Anandamide is found in nearly all tissues in a wide range of animals¹. It's also been found in plants, including small amounts in chocolate¹. The name 'anandamide' is taken from the Sanskrit word Ananda, which means "joy, bliss, delight", plus amide¹. Anandamide is derived from the non-oxidative metabolism of arachidonic acid, an essential omega-6 fatty acid¹. It is synthesized from N-arachidonoyl phosphatidylethanolamine by multiple pathways¹. Anandamide's effects can occur in either the central or peripheral nervous system. These distinct effects are mediated primarily by CB1 cannabinoid receptors in the central nervous system, and CB2 cannabinoid receptors in the periphery¹. For more detailed information, you can refer to the [Wikipedia page on Anandamide] (^1^) or the [article on Be Brain Fit] (^2^). These sources provide comprehensive information about the structure, function, and role of Anandamide in the human body. Source: Conversation with Bing, 3/17/2024 (1) Anandamide - Wikipedia. https://en.wikipedia.org/wiki/Anandamide. (2) Anandamide - Wikipedia. https://en.wikipedia.org/wiki/Anandamide. (3) Anandamide: Bliss Molecule for Happiness & Mental Balance. https://bebrainfit.com/anandamide/. (4) Anandamide Definition & Meaning - Merriam-Webster. https://www.merriam-webster.com/dicti.... (5) What is Anandamide and how does it work? | Kalapa Clinic. https://www.kalapa-clinic.com/en/what....