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A lipoma is a lump under the skin that occurs due to an overgrowth of fat cells. However, people may wish to remove a lipoma that causes pain, complications, or other symptoms. Some people also have concerns about the cosmetic appearance of lipomas. Lipomas can occur anywhere on the body where fat cells are present, but they tend to appear on the shoulders, chest, trunk, neck, thighs, and armpits. In less common cases, they may also form in internal organs, bones, or muscles. Lipomas feel soft and may move slightly under the skin when people press down on them. They usually grow slowly over a period of months or years and typically reach a size of around 2–3 centimeters (cm)Trusted Source. Occasionally, people have giant lipomas , which can grow to more than 10 cm. Some people inherit a faulty gene from their parents that can cause one or more lipomas. This is rare and is known as familial multiple lipomatosis. Lipomas can occur more frequently in people with specific medical conditions, such as: Gardner’s syndrome Cowden syndrome Madelung’s disease adiposis dolorosa also suggested that some lipomas may result from an injury that involves a substantial impact on the area. Symptoms A person with a lipoma will typically feel a soft, oval-shaped lump just beneath the skin. Lipomas are usually painless unless they affect joints, organs, nerves, or blood vessels. In most cases, they do not cause other symptoms. A person with a lipoma that occurs deeper under the skin may not be able to see or feel it. However, a deep lipoma may place pressure on internal organs or nerves and cause associated symptoms. For example, a person with a lipoma on or near the bowels may experience nausea, vomiting, and constipation. Health implications Lipomas are benign masses of fat cells. However, experts disagree about whether or not lipomas have the potential to become cancerous. A cancerous mass of fat cells is known as a liposarcoma. many experts have concluded that liposarcomas do not develop from lipomas but are, in fact, a different type of tumor. They believe that doctors sometimes mistake liposarcomas for lipomas. It is fairly common for a person to develop a lipoma. Experts estimate that around 1 percent of people have a lipoma. People who have a family relative with one or more lipomas have a higher risk of developing this condition. Lipomas are also more likely to occur in people aged between 40 and 60 years old Other risk factors for developing a lipoma may include: obesity high cholesterol diabetes liver disease glucose intolerance These changes might involve the lipoma: increasing in size or suddenly growing very quickly being painful becoming red or hot turning into a hard or immovable lump causing visible changes in the overlying skin Doctors can usually diagnose a lipoma with a simple physical examination. They may start by inspecting and feeling the lump. If the lipoma is large or painful, the doctor may order tests to check if it is cancerous. They may use the following tests: biopsy, where the doctor will remove a small sample of cells from the lump and examine the tissue under a microscope to look for signs of cancer ultrasound scan MRI scan CT scan