Anti-Cancer Drug Development by Tumor Explants | Protocol Preview скачать в хорошем качестве

Anti-Cancer Drug Development by Tumor Explants | Protocol Preview

Watch the Full Video at https://www.jove.com/v/2846/method-fo.... Method for Novel Anti-Cancer Drug Development using Tumor Explants of Surgical Specimens - a 2 minute Preview of the Experimental Protocol Kaushal Joshi, Habibe Demir, Ryosuke Yamada, Takeshi Miyazaki, Abhik Ray-Chaudhury, Ichiro Nakano The Ohio State University Medical Center, Department of Neurological Surgery; The Ohio State University Medical Center, Department of Pathology; Here, we established a method for drug efficacy testing with surgical specimens of brain tumors, termed “tumor explant method”. With this method, we can evaluate drug efficacy without breaking the microenvironment of solid tumors. To validate reliability of this method, we describe representative data with our glioma specimen treated with the current first-line chemotherapeutic agent, temozolomide. Visit https://www.jove.com?utm_source=youtu... to explore our entire library of 14,000+ videos of laboratory methods and science concepts. JoVE is the world-leading producer and provider of science videos with the mission to improve scientific research and education. Millions of scientists, educators, and students at 1500+ institutions worldwide, including schools like Harvard, MIT and Stanford benefit from using JoVE's extensive library of 14,000+ videos in their research,education and teaching. Subscribe to our channel:    / jovejournalofvisualizedexperiments