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🎙️ Episode 12 - AI vs. Delirium: Saving Brains & Billions in Healthcare with John Klepper (PIPRA) In this episode of the ReeThink Podcast*, host Rudi Adigbli speaks with *John Klepper*, co-founder of *PIPRA*, about how *AI in healthcare is being used to predict delirium before surgery, saving hospitals millions and protecting long-term brain health. You’ll learn why delirium affects *1 in 4 patients over 60*, how a single episode can increase *dementia risk by 1400%*, and why this “silent epidemic” costs more than diabetes in the US healthcare system. Beyond the medical breakthrough, this conversation explores the reality of building a *MedTech startup*: regulatory hurdles, selling innovation to hospitals, and why culture beats CVs when building high-performing teams. From AI-driven surgical workflows to the broader risks of automation and job displacement, this episode offers a grounded, real-world view of the future of *AI in medicine*. 00:00 Introduction — Who is John Klepper? 04:57 Why Hospitals Care About Delirium (Not Dementia) 09:18 40% Mortality & 1400% Dementia Risk Explained 15:17 The Silent Epidemic: Hypoactive Delirium 20:01 How PIPRA’s AI Integrates Into Surgery 28:26 Why Delirium Costs More Than Diabetes 30:05 The MedTech Grind: Regulation & Reality 36:14 Hiring for Grit, Culture & Values 48:33 The AI Paradox: Medical Cures vs Job Displacement 🎧 Listen on: Apple podcast: https://podcasts.apple.com/us/podcast... Spotify: https://open.spotify.com/episode/7rFK... 👉 Read the full episode summary on my Substack: [https://reethink.substack.com/?r=5rf5...] 👉 Join The ReeShaper Circle to connect with others shaping the neurotech industry: [https://www.skool.com/fundrazr-3557/a...] #AIinHealthcare #Delirium #Neurotech #DigitalHealth #MedTech #BrainHealth #HealthcareInnovation