HPLC: Kynurenine & Kynurenic Acid: Relate Biochemistry: Cognition & Sleep In Rats l Protocol Preview скачать в хорошем качестве

HPLC: Kynurenine & Kynurenic Acid: Relate Biochemistry: Cognition & Sleep In Rats l Protocol Preview

Watch the Full Video at https://www.jove.com/v/58129/a-high-p.... A High-performance Liquid Chromatography Measurement of Kynurenine and Kynurenic Acid: Relating Biochemistry to Cognition and Sleep in Rats - a 2 minute Preview of the Experimental Protocol Annalisa M. Baratta, Shaun S. Viechweg, Jessica A. Mong, Ana Pocivavsek University of Maryland School of Medicine, Maryland Psychiatric Research Center, Department of Psychiatry; University of Maryland School of Medicine, Department of Pharmacology; Alterations in the kynurenine pathway (KP) neuroactive metabolites are implicated in psychiatric illnesses. Investigating the functional outcomes of an altered kynurenine pathway metabolism in vivo in rodents may help elucidate novel therapeutic approaches. The current protocol combines biochemical and behavioral approaches to investigate the impact of an acute kynurenine challenge in rats. Visit https://www.jove.com?utm_source=youtu... to explore our entire library of 14,000+ videos of laboratory methods and science concepts. JoVE is the world-leading producer and provider of science videos with the mission to improve scientific research and education. Millions of scientists, educators, and students at 1500+ institutions worldwide, including schools like Harvard, MIT and Stanford benefit from using JoVE's extensive library of 14,000+ videos in their research,education and teaching. Subscribe to our channel:    / jovejournalofvisualizedexperiments