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#drnajeeb #medicines #pharmacology #medicaleducation #drnajeeblectures #basalganlia #neuroscience Basal Ganglia | Structure Function | Neuroanatomy | Dr Najeeb Like this video? Sign up now on our website at https://www.DrNajeebLectures.com to access 1000+ Exclusive videos on Basic Medical Sciences & Clinical Medicine. These are premium videos (NOT FROM YOUTUBE). All these videos come with English subtitles & download options. Sign up now! Get Lifetime Access for a one-time payment of $99 ONLY! Sign up now on our website at https://bit.ly/SpecialOffer45 --------------------------------------------------------------------------------------------------------------------------- Why sign up for premium membership? Here's why! Membership Features for premium website members. 1. More than 1000+ Medical Lectures. 2. Basic Medical Sciences & Clinical Medicine. 3. Mobile-friendly interface with android and iOS apps. 4. English subtitles and new videos every week. 5. Download option for offline video playback. 6. Fanatic customer support and that's 24/7. 7. Fast video playback option to learn faster. 8. Trusted by over 2M+ students in 190 countries. --------------------------------------------------------------------------------------------------------------------------- 00:00:00 Basic anatomy, location of Thalami, Caudate and Lentiform nuclei and Internal Capsule, and other structures in the base of the brain 00:12:47 Insula, Putamen, Globus Pallidus, Subthalamus, Midbrain, Superior and inferior colliculi, Substantia Nigra, Amygdala 00:19:29 Basal Ganglia classification: Traditional and Clinical 00:23:55 Corpus Striatum, Neo Striatum, Paleo striatum classification, Lentiform nucleus 00:29:10 Corticospinal fibers, Corticonuclear/Corticobulbar fibers 00:37:11 Initiation of idea/message: Prefrontal cortex, Primary, pre-and supplementary motor areas 00:40:20 Corticostriatal pathway-(up to)-Thalamocortical pathway 00:44:35 Neurotransmitters; Glutaminergic, GABAergic fibers/neurons, Increased firing of Inhibitory/GABAergic fibers at times of motor rest and vice versa; [Direct pathway] 00:57:15 Indirect pathway [involves subthalamus]; Glutaminergic pathway, 01:05:47 Substantia Nigra, Role of Dopaminergic fibers [Nigrostriatal pathway], Initiation of movement, its role in balance and fine-tuning through controlling of the previous two pathways. Counter-balancing act of Cholinergic neurons. 01:31:25 Summary/Revision of all pathways and structures. 01:35:35 Basal Ganglia Lesions [Direct Pathway lesions] causing Hypokinesia: Parkinsonism & Parkinson's Disease: Masked Facial Expressions, Serpentine Look, Lead pipe Rigidity and Pin Rolling Resting Tremors. 01:51:06 Drugs induced Parkinsonism: MPTP-associated Parkinson's, role of Dopamine Receptor blockers (Antipsychotic drugs) 01:53:06 Basal Ganglia Lesions [Indirect Pathway lesions] causing Hyperkinesia/Dyskinesia: Huntington's Disease. 01:59:30 Hyperkinesia; further explained: Chorea; Huntington's chorea, St. Viton’s' dance/Sydenham chorea, Wilson's Disease/Hepatolenticular Disease 02:12:34 Hyperkinesia; continued: Athetosis, Choreoathetosis, Dystonia, Ballismus/Hemiballismus, Tardive Dyskinesias (Dopamine Receptor Blockers use) 02:23:21 Rapid review of a full lecture. --------------------------------------------------------------------------------------------------------------------------- Join this channel to get access to perks: Sign up now on our website at https://members.drnajeeblectures.com/... / @doctornajeeb Follow us on Facebook :- / drnajeeb Follow us on Instagram :- / drnajeeblectures