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This webinar will focus on the analytical methods and procedures being developed at NIST for accurately measuring cannabinoids (THC, THCA, CBD, etc.) in Cannabis samples and the solutions provided by Shimadzu Scientific Instruments. NIST has started screening hemp plant and oil materials for 11 cannabinoids through the combination of liquid chromatography and a photodiode array detector (LC-PDA). Samples are extracted with methanol following the protocols approved in an AOAC Official Analytical Method for the quantitation of cannabinoids in Cannabis plant, concentrates, and oils. Samples at NIST are being analyzed using the external calibration approach for THC, THCA, and total THC with the “Cannabis Analyzer” from Shimadzu. After initial screenings, potential hemp RMs and CannaQAP materials will be well characterized using isotope dilution (ID) gas chromatography – mass spectrometry (GC-MS) and LC with tandem mass spectrometry (MS/MS).