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When managing hyponatremia, the primary concern (at least as far as I have always been taught) is osmotic demyelination syndrome. We are warned not to correct the sodium too quickly, because the neurologic outcome can be awful. However, demyelination is very rare, and apparently there is a lot of data that suggests correcting sodium too slowly can increase mortality! Full blog post: https://first10em.com/big-practice-ch... Some other resources: https://www.nephjc.com/news/hyponatre... https://ajkdblog.org/2024/03/01/nephm... First10EM is a free open access medical education (FOAMed) platform created and run by Dr. Justin Morgenstern dedicated to high quality education focused on resuscitation and evidence based medicine. Website: https://first10em.com/ Resuscitation: http://resus.first10em.com/ Evidence based medicine: https://ebm.first10em.com/ Twitter: @First10EM / first10em Facebook: / first10em Instagram: / first10em Bluesky: @first10em.bsky.social https://bsky.app/profile/first10em.bs... TikTok: / first10em Reddit: / first10em First10EM is devoted to free, open access medical education, aimed at medical professionals. The website does not provide specific medical advice. I may be a physician, but I am not your physician. If you are a medical professional, the information should be used like any other you encounter: think critically, consider other sources of information, and ensure that you understand how the information presented here fits with your own skills, work environment, and resources. Full disclaimer: https://first10em.com/disclaimer/ I have never accepted money from any drug or device company. I have no financial conflicts of interest in any information I present. Thank you for watching! 🙂