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We can divide abdomen with 4 imaginary quadrant. Following organs are located In the Right lower quadrant: appendix, the upper portion of the colon, and the right ovary and the Fallopian tube in women. Generally, abdominal pain is common and most cases are mild, without any serious underlying cause. In Most cases abdominal pain is caused by indigestion, gas, constipation, muscle spasm, muscle strain or gastritis. But when pain is severe and located, specifically on right lower quadrant of abdomen, then most common cause is appendicitis. Appendicitis is inflammation of the appendix. Appendix is a part of intestine. Treatment of appendicitis surgical removal of appendix and it is called appendectomy. Appendectomy is the most common surgical operation of abdomen. Appendicitis has its highest incidence between the ages of 10 and 30 years. Untreated, appendicitis can lead to perforation of the appendix, which typically occurs within 24 to 36 hours of the onset of symptoms. Perforation of the appendix can cause intra-abdominal infection, sepsis, intraperitoneal abscesses, and rarely death. In order to avoid the sequelae of perforated appendicitis, a low percentage of “negative” appendectomies is generally accepted from a surgical standpoint. If we suspect appendicitis surgical consultation should be provided, without any delay. And we can suspect on appendicitis with the following symptoms: abdominal pain migrating to the right lower quadrant (RLQ), Pain from appendicitis may begin as dull pain around the navel. After several hours, pain will usually transition towards the right lower quadrant, where it becomes localized. anorexia, fever, and nausea/vomiting. On examination, RLQ tenderness (hard), along with “classical” signs of peritoneal irritation (e.g., rebound tenderness, guarding, rigidity, referred pain). Rebound tenderness, also known as Blumberg's sign, refers to the presence of pain when pressure is removed from the abdomen, rather than when applied. Abdominal guarding is the tensing of the abdominal wall muscles to guard inflamed organs within the abdomen from the pain of pressure upon them. The tensing is detected when the abdominal wall is pressed. although many patents can have atypical presentation, so appendicitis can possible partial or without abomination symptoms. Imaging tests, such as ultrasound (US), computed tomography (CT) with and without contrast, and magnetic resonance imaging (MRI), are also used extensively for the diagnosis of appendicitis. Among Women, other serious causes of lower right abdominal pain can be ovarian cyst rupture, or adnexal torsion. Other causes can be: Kidney stones, kidney infection, hernia, rarely, inflammatory bowel disease (IBD), irritable bowel syndrome (IBS). By BruceBlaus. When using this image in external sources it can be cited as:Blausen.com staff (2014). "Medical gallery of Blausen Medical 2014". WikiJournal of Medicine 1 (2). DOI:10.15347/wjm/2014.010. ISSN 2002-4436. - Own work, CC BY 3.0, https://commons.wikimedia.org/w/index... By OpenStax - https://cnx.org/contents/[email protected]... 8.25 from the TextbookOpenStax Anatomy and PhysiologyPublished May 18, 2016, CC BY 3.0, https://commons.wikimedia.org/w/index... By Adert - File:Dickdarm-Schema.svg, CC BY-SA 3.0, https://commons.wikimedia.org/w/index... By http://www.scientificanimations.com/ - http://www.scientificanimations.com/w..., CC BY-SA 4.0, https://commons.wikimedia.org/w/index... By Steven Fruitsmaak - I, Steven Fruitsmaak, am the creator. Based upon Image:A nude man standing.jpg, by Jasonz, which is GFDL. Edited with Adobe Photoshop., CC BY-SA 3.0, https://commons.wikimedia.org/w/index...