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In this insightful episode on Psychiatry Simplified, Dr. Sanil Rege, a Consultant Psychiatrist, takes us through the nuanced and often overlooked effects of alcohol on the brain. The video not only explores the biochemical mechanisms of alcohol from a scientific standpoint but also discusses its broader implications on mental health and societal norms. Beginning with genetic predispositions to alcohol dependence, Dr. Rege explains how our DNA can dictate our relationship with alcohol, affecting as much as 64% of the population. As we dive deeper, Dr. Rege discusses the hijacking of the brain's reward system by alcohol through alterations in neurotransmitter systems like dopamine and GABA. He brings to light the dual role of alcohol as both an activator and an inhibitor, enhancing certain neural activities while suppressing others, leading to a complex interplay that can result in addiction and withdrawal symptoms. Understanding the role of neurotransmitters such as glutamate and the opioidergic system, Dr. Rege elaborates on how alcohol impacts long-term learning, pleasure responses, and even direct neuronal toxicity. With compelling explanations and clear visuals, the video delves into the physiological changes induced by alcohol, including oxidative stress, glutamate excitotoxicity, and thiamine depletion, which can lead to severe neurological conditions like Wernicke-Korsakoff syndrome. This video is a must-watch for anyone interested in the psychological, neurological, and social dimensions of alcohol use. Don't forget to subscribe to Psychiatry Simplified for more insightful videos that help demystify complex psychiatric topics. If you find this video educational, hit the like button and share your thoughts in the comments section below. Let us know what other topics you would like Dr. Rege to cover in future videos. Thank you for watching, and stay curious as we continue to explore the fascinating world of psychiatry and neurosciences together. #AlcoholImpact #BrainHealth #Neurotransmitters #Dopamine #GABA #Glutamate #NeuronalToxicity #OxidativeStress #MentalHealth #Neuroscience #PsychiatrySimplified #DrSanilRege #AddictionRecovery #WithdrawalSymptoms #WernickeKorsakoffSyndrome #ModerateDrinking #PsychiatricEducation Relevant Resources: 👉https://www.academy.psychscene.com Related Videos 👉ALCOHOL & WERNICKE-KORSAKOFF SYNDROME | BRAIN DISORDER caused by Thiamine (Vitamin B1) Deficiency • ALCOHOL & WERNICKE-KORSAKOFF SYNDROME | BR... 🎓RESOURCES BY PSYCH SCENE: 🌐The Academy by Psych Scene: PSYCHIATRY EDUCATION REDEFINED https://academy.psychscene.com/ Revolutionary psychiatry learning. 🌐Psych Scene Hub: PSYCHIATRY TEXTBOOK OF THE FUTURE https://psychscenehub.com/ The Hub is devoted to making you a better mental health professional. Our team of academic and clinical experts bring you powerful summaries, videos and interviews in psychiatry and neurosciences. 🌐Psych Interview Online: REAL WORLD SKILLS FOR REAL WORLD SUCCESS https://www.psychinterview.com/ The Psych Interview online courses offer high-quality training to help you improve your psychiatric interview skills through self-study. 🌐Psych Scene Online: THE ONLINE COURSES TO HELP YOU SUCCEED https://ranzcpexams.psychscene.com/ Learn at your own pace with the RANZCP Written Exam prep online courses. 🌐Psych Scene: THE PSYCHIATRY TRAINING EXPERTS https://psychscene.com/ Psych Scene offers specialised training and professional development for Psychiatry Trainees, Psychiatrists, General Practitioners and Mental Health Practitioners. -- 📱SOCIALS Subscribe for weekly videos on Psychiatry and Neuroscience: Facebook: / psychscenehub Instagram: / psychiatry.excellence – 👋 LET’S CONNECT! Follow Sanil Rege on LinkedIn: / sanilrege