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Keith Desserich from The Cure Starts Now and Dr. Trent Hummel discuss the causes of DIPG, environmental clustering and general age range of patients. Learn more at https://dipg.org/dipg-facts/causes-of... Researchers do not yet know what causes DIPG. Like most cancers, DIPG occurs when something goes wrong with the process of cell reproduction. However, unlike many other cancers, there is no evidence that indicates DIPG is caused by environmental factors (exposure to chemicals or radiation), or specific inherited genetic variations. Cells use DNA, the building blocks of genes, in order to carry out various functions, including making more cells. Sometimes pieces of DNA become damaged or are copied incorrectly. Scientists call this a mutation. Usually, cells with mutations in their DNA either repair the mutation or die (a process called apoptosis). Sometimes, though, cells with mutations can’t be repaired and don’t die like they are supposed to. In certain cases, these mutated cells begin to divide quickly, which may cause a person to develop cancer.