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Join Nurse Kelly Nwankiti, Lead Nurse for Patient Blood Management at King’s College Hospital, as she explains the key details of blood transfusions — who they’re for, why they’re needed, and what’s involved in the process. In this clear and informative presentation, Nurse Kelly also answers common patient questions, helping to make this complex topic easier to understand. 0:00 Introduction 0:36 MDS & CMML overview 0:55 How blood cells are made (hematopoiesis) 4:02 What are cytopenias? (low levels of cells) 5:35 How cytopenias are treated (transfusion) 6:52 Other treatments for cytopenias: G-CSF, TPO/eltrombopag, EPO 7:54 When to transfuse: triggers & thresholds, symptoms & resources 11:34 Platelet transfusions: triggers vs targets 15:22 Platelets for procedures & active bleeding 17:50 Red cell transfusions: thresholds & individualized targets 22:29 Benefits of tranfusion vs risks 23:53 Iron overload & iron chelation 25:21 Loss of response: refractoriness & diminishing benefit 26:58 Blood shortages & stewardship (why supply matters) 30:32 Questions from patients: triggers, BP/fatigue, thresholds, advocacy & “fresh” blood This talk was recorded during an MDS UK Online Support Meeting, offering valuable insights for anyone living with MDS (Myelodysplastic Syndromes) or supporting someone who is. For more information and patient resources, visit: https://mdspatientsupport.org.uk