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In Part 2 of this series, we build on the biology discussed in Part 1 and explore how obesity connects to cardiometabolic disease, sleep apnea, chronic inflammation, and long-term health risk. I share my own experience — now over 20 weeks into my GLP-1 journey — and how these medications changed far more than my weight. They changed my biology, helping move me out of metabolic syndrome and into a more stable, healthier state. This discussion is grounded in decades of research, including randomized controlled trials and meta-analyses, showing that GLP-1 medications do much more than suppress appetite. They help restore clearer metabolic signaling — making sustainable lifestyle changes possible again for many people. GLP-1s are not right for everyone, and this is not medical advice. But if any of this resonates with you, I encourage you to talk with your doctor about your metabolic health and available options.