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COVID-19 has emphasized the importance of medical research the world over. In India, the Indian Council of Medical Research has not only been helming bio-medical and health research since its inception in 1911, but the organization has been periodically updating the guidelines since 1980, to address ethical concerns around different forms of biomedical and health research that impact human beings. ICMR’s National Ethical Guidelines address a range of discussions often raised in public forums around biomedical research. The guideline has covered some newer areas like: Let’s have a closer look at what each of the 12 sections talk about The Statement of General Principles lays down the guidelines that need to be followed to conduct health research – highlighting these 4 basic principles that protect the dignity, rights, safety and well-being of research participants