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Warning: This video contains actual surgical footage which may not be suitable for all viewers. Alan Kominsky, MD discusses The Inspire® Upper Airway Stimulation (UAS) system that has become a common therapeutic option for patients with obstructive sleep apnea (OSA) but intolerant of continuous positive airway pressure (CPAP). He also discusses the recent FDA approval of the two incision method which makes recovery easier and less painful for patients. Chapters: 0:00 Introduction 0:07 Cleveland Clinic 1:28 Disclosures 2:26 CPAP Adherence and Acceptance 4:22 Why Surgery? 5:27 Physical Exam 7:01 Outline 7:06 Surgical Intervention 8:30 Traditional UPPP 10:09 Surgical Treatment 17:13 Hypoglossal Nerve Stimulaton 19:17 Inspire Upper Airway Stimulation TM System 22:33 Drug Induced Sleep Endoscopy DISE 28:26 Nerve Identification 29:24 Cuff Placement 30:35 Inspire Upper Airway Stimulation System 30:49 Post Operative Course 34:40 Troubleshooting 36:08 Complications 42:21 5 Year Outcomes-STAR Trial 44:16 ADHERE Registry 47:14 Outcome Predictors 50:10 Future Options for Inspire 51:03 Current Options for Inspire 51:18 2 Incision Technique 53:17 Wish List 54:42 Alternate Device 56:25 Future Direction 57:40 Takeaways Dr. Kominksy is an otolaryngologist and sleep specialist as well as the section director of the Head & Neck Institute's surgical sleep and snoring program at Cleveland Clinic. To learn more about him, please visit https://cle.clinic/2IFebav Moderated by Jamie Ku, MD, Director of the Head and Neck Robotic Surgery Program at Cleveland Clinic. To learn more about her, please visit https://cle.clinic/2W5K2ZN If you liked the video hit like and subscribe for more! #clevelandclinic #hnilive #medicaleducation #headandneck