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This video aims at teaching new surgeons the basic principles and techniques of surgery with an emphasis on rodents. Watch the full video at https://www.jove.com/v/2586/principle..., no sign up needed for open access content, or request a trial to get instant access to our full library. This video gives a hands on training of the preparatory steps of a successful rodent surgery. It also talks about the pre and post operative considerations and monitoring during a surgery. Visit https://www.jove.com/?utm_source=yout... to explore our entire library of 14,000+ videos of laboratory methods and science concepts. JoVE is the world-leading producer and provider of science videos with the mission to improve scientific research and education. Millions of scientists, educators, and students at 1500+ institutions worldwide, including schools like Harvard and the University of Cambridge, benefit from using JoVE’s extensive library of 14000 videos in their research and teaching. Follow JoVE on Twitter: / jovejournal Like JoVE on Facebook: / jovejournal Subscribe to our channel: / jovejournalofvisualizedexperiments