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Vaginal Microbiome and Immunity

Presented By: Smita Gopinath, PhD Speaker Biography: Smita is an Assistant Professor in the Department of Immunology and Infectious Diseases in the Harvard School of Public Health. Her research group studies the vaginal microbiome, using mouse models investigating the basic mechanisms of the unique bacterial communities found in our vaginal mucosa to understand community interactions and their effect on immune homeostasis and resistance to sexually transmitted infections. Webinar: Vaginal Microbiome and Immunity Webinar Abstract: Mammalian mucosal niches are colonized by a complex ecosystem of viruses, bacteria and fungi termed the microbiome. Unlike the gut microbiome, the vaginal microbiome is composed of small number of bacterial species and is consistently found in people around the world. The bacterial communities fall into lactobacilli-dominant, low diversity communities and lactobacilli-low high diversity communities. In contrast to other mucosal niches, high-diversity communities are associated with increased acquisition of sexually transmitted infections and poor pregnancy outcomes including preterm birth. Determining the contribution of the microbiome to mucosal immunity is critical to designing new therapeutics and vaccine techniques. We will discuss the prime and pull vaccine technique, which leverages a commonly-used antibiotic increase antiviral immunity at the vaginal mucosa. Earn PACE Credits: 1. Make sure you’re a registered member of Labroots (https://www.labroots.com/) 2. Watch the webinar on YouTube or on the Labroots Website (https://www.labroots.com/ms/webinar/v...) 3. Click Here to get your PACE credits (Expiration date – 09/07/2024): https://www.labroots.com/credit/pace-... Labroots on Social: Facebook:   / labrootsinc   Twitter:   / labroots   LinkedIn:   / labroots   Instagram:   / labrootsinc   Pinterest:   / labroots   SnapChat: labroots_inc